Endocrine Abstracts

Introduction: Hypocalcaemia secondary to post-operative hypoparathyroidism is a recognised complication of thyroid surgery with reported rates of up to 75%. Little guidance exists on the appropriate management of post-operative hypocalcaemia and individual clinicians may develop their own preferred management strategies based on past experience. However, delay in restoring normocalcaemia may increase length of hospital stay and patient morbidity.Aims: i)...

Background and aims: The high prevalence of diabetes and IGTT in women of childbearing age in our community provides an opportunity to assess prospectively the risks of adverse outcome in pregnancy of these conditions.Method: This retrospective analysis data of a 114 pregnant women diagnosed to have gestational impaired glucose tolerance test, in the period from beginning of January 2001 to the end of December 2004 from maternal & neonatal documents,...

The aim of this study was to examine the indications, the surgical result and the complications rate after thyroidectomy for patients aged 70 and over.Material and methods: Retrospective analysis of 46 patients underwent thyroid surgery at District General Hospital.Results: Micronodular goitre/20 patients/toxic thyroid/7 patients, and suspected malignancy/19 patients/was indication for surgery.Twenty-four pat...

Tribulus terrestris (TT) is used in the Arabic folk medicine to Q1 treat various diseases. The aim of this study was to investigate the protective effects of TT in diabetes mellitus (DM). Diabetes is known to increase reactive oxygen species (ROS) level that subsequently contributes to the pathogenesis of diabetes. Rats were divided into six groups and treated with either saline, glibenclamide (Glib), or TT for 30 days. Rats in group 1 were given sa...

Over a third of women with polycystic ovarian syndrome (PCOS) display glucose intolerance and multiple risk factors for cardiovascular disease, including central obesity. Interleukin-6, a cytokine that is mainly derived from adipose tissue, has recently been implicated as an important link in the development of cardiovascular disease in obesity. We determined the relations between circulating Interleukin-6 levels and anthropometric, metabolic and hormonal parameters in 38 wome...

IntroductionRecent studies in patients with Addison’s disease have shown that this condition, even if treated, is fraught with significant morbidity and even excess mortality. The objective of our study was to determine the deleterious effects of long-term glucocorticoid replacement mainly on the metabolic level.MethodsRetrospective study, carried out at the Endocrinology and Diabetology Department of H&...

IntroductionRecent studies in patients with Addison’s disease (AD) have shown that this condition, even if treated, is fraught with significant morbidity. In this context, we report a retrospective study which concerned 32 patients with AD in order to determine the deleterious effects of long-term glucocorticoid substitution, mainly on the occurrence of type 2 diabetes.ResultsIn the 32 patients followed ...

IntroductionThe synthetic anti-oestrogen tamoxifen is the endocrine treatment modality most commonly used for therapy of hormone sensitive breastcancer. The influence of tamoxifen on thyroid function has not been fully elucidated.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular signs. She presented firstly a s...

IntoductionThe link between hyperthyroidism and breast cancer has been the subject of much controversy and literature in the past. It poses a daily clinical problem of information and senological follow-up of thyroid patients. We report our patient’s case.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular s...

Hashimoto’s thyroiditis is the most common cause of hypothyroidism in iodine-sufficient areas of the world, cause is thought to be a combination of genetic susceptibility and environmental factors. The pathology of the disease involves the formation of antithyroid antibodies that attack the thyroid tissue, causing progressive fibrosis. We present the case of a 38 year old male with history of hypertension, type 2 Diabetes and pre-existing hypothyroidism who presented with...